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| dc.contributor.author | Kalansuriya, P. | |
| dc.contributor.author | Quezada, Michelle | |
| dc.contributor.author | Espósito, Breno P. | |
| dc.contributor.author | Capon, Robert J. | |
| dc.date.accessioned | 2023-09-11T05:37:59Z | |
| dc.date.available | 2023-09-11T05:37:59Z | |
| dc.date.issued | 2017-03-24 | |
| dc.identifier.citation | Kalansuriya, P., Quezada, M., Esposito, B. P., & Capon, R. J. (2017). Talarazines A–E: Noncytotoxic iron (III) chelators from an Australian mud dauber wasp-associated fungus, Talaromyces sp.(CMB-W045). Journal of Natural Products, 80(3), 609-615. | en_US |
| dc.identifier.uri | http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14551 | |
| dc.description.abstract | ABSTRACT: Chemical analysis of an Australian mud dauber wasp-associated fungus, Talaromyces sp. (CMB-W045), yielded five new coprogen siderophores, talarazines A−E( 1−5), together with dimerumic acid (6), desferricoprogen (7), and elutherazine B (8). Structures inclusive of absolute configuration were assigned on the basis of detailed spectroscopic analysis and application of the C3 Marfey’s method. We report on the noncytotoxic Fe(III) chelation properties of 1−8 and demonstrate that biosynthesis is regulated by available Fe(III) in culture media. We demonstrate a magnetic nanoparticule approach to extracting high-affinity Fe(III) binding metabolites (i.e., 8) from complex extracts. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | American Chemical Society and American Society of Pharmacognosy | en_US |
| dc.title | Talarazines A−E: Noncytotoxic Iron(III) Chelators from an Australian Mud Dauber Wasp-Associated Fungus, Talaromyces sp. (CMB-W045) | en_US |
| dc.type | Article | en_US |
