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| dc.contributor.author | Shang, Zhuo | |
| dc.contributor.author | Khalil, Zeinab G. | |
| dc.contributor.author | Li, Li | |
| dc.contributor.author | Salim, Angela A. | |
| dc.contributor.author | Quezada, Michelle | |
| dc.contributor.author | Kalansuriya, P. | |
| dc.contributor.author | Capon, Robert J. | |
| dc.date.accessioned | 2023-09-13T05:13:07Z | |
| dc.date.available | 2023-09-13T05:13:07Z | |
| dc.date.issued | 2016-08-18 | |
| dc.identifier.citation | TY - JOUR T1 - Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions AU - Shang, Zhuo AU - Khalil, Zeinab AU - Li, Li AU - Salim, Angela A. AU - Quezada, Michelle AU - Kalansuriya, Pabasara AU - Capon, Robert J. Y1 - 2016/09/02 PY - 2016 DA - 2016/09/02 N1 - doi: 10.1021/acs.orglett.6b02099 DO - 10.1021/acs.orglett.6b02099 T2 - Organic Letters JF - Organic Letters JO - Org. Lett. SP - 4340 EP - 4343 VL - 18 IS - 17 PB - American Chemical Society SN - 1523-7060 M3 - doi: 10.1021/acs.orglett.6b02099 UR - https://doi.org/10.1021/acs.orglett.6b02099 ER - | en_US |
| dc.identifier.uri | http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14621 | |
| dc.description.abstract | Cultures of the estuarine fungus Penicillium roseopurpureum (CMB-MF038) yielded a diverse array of polyketides, many of which were related via a highly convergent biosynthetic pathway. In addition to revising and assigning structures, and documenting chemical and biological properties, pro-drug cytotoxic properties were attributed to roseopurpurins H (10) and I (11) on the basis of in situ reverse Michael addition to a cytotoxic Michael acceptor (12). | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | ACS Publications | en_US |
| dc.title | Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions | en_US |
| dc.type | Article | en_US |
